Gall bladder mucosal epithelial hyalinosis

Research Services

Round cell tumor proliferation in the bone marrow of a research mouse (hematoxylin eosin stain).
Round cell tumor proliferation in the bone marrow of a research mouse (hematoxylin eosin stain).

Welcome to the Comparative Pathology Laboratory, where our team of experts is ready to support your research endeavors. We provide a comprehensive range of services for both UC and external investigators including:

1. Necropsy services for study animals, encompassing gross dissection of target tissues, organ weights, and high-quality photo documentation as needed.

2. Tissue processing and histopathologic interpretation conducted by our ACVP board-certified veterinary pathologists. We offer semi-quantitative data analysis and photomicroscopy as required.

3. Blood collection and processing for hematology and serum biochemistry, specializing in low sample volumes. Collection of other samples during necropsy for downstream assays is available.

4. Pre-study consultation services covering experimental design, animal modeling, and optimal sample collection strategies.

5. Generation of publication-ready figures and text to enhance the scientific quality and dissemination of your research findings.

6. We specialize in morphologic phenotyping of rodents, translational studies in geropathology and infectious diseases, models of immunotherapy in humanized mice (including CAR T cells), genetic therapy (including AAV), pre-clinical studies in oncology, degenerative diseases, and many others.

For further information on how we can support your project, please reach out to us at cpl-projects@ucdavis.edu. We look forward to collaborating with you. 

Human histiocytic cells proliferation in the cerebellum of a research mouse (anti-human mitochondria immunohistochemistry).
Human histiocytic cell proliferation in the cerebellum of a humanized mouse (anti-human mitochondria immunohistochemistry).

 

Digital analysis
Example of digital image analysis for between-group comparisons.

 

Dr. Denise Imai-Leonard DVM, PhD, DACVP https://orcid.org/0000-0003-0667-2054

Dr. Pedro Ruivo DVM, MS, DACVP https://orcid.org/0000-0002-5419-4790